Sentinel lymph node mapping in endometrial cancer: an updated review Abstract
Jacqueline HS LEE 1, Joshua JX LI 2
1 Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong
2 Department of Anatomical and Cellular Pathology, Faculty of Medicine, The Chinese University of Hong Kong
Sentinel lymph node mapping (SLNM) is widely used in staging of both low- and high-risk early-stage endometrial cancer. It has a high detection rate, high sensitivity, high negative predictive value, and low false negative rate in detection of lymph node metastasis. Cervical injection of indocyanine green for SLNM is the preferred method. SLNM reduces the number of lymph node removal and reduces complications from lymphadenectomy without compromising oncological safety. This review discusses the latest evidence of SLNM in endometrial cancer staging in terms of technique, accuracy, limitations, impact on lymphadenectomy complications, and cancer survival.
1 Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong
2 Department of Anatomical and Cellular Pathology, Faculty of Medicine, The Chinese University of Hong Kong
Sentinel lymph node mapping (SLNM) is widely used in staging of both low- and high-risk early-stage endometrial cancer. It has a high detection rate, high sensitivity, high negative predictive value, and low false negative rate in detection of lymph node metastasis. Cervical injection of indocyanine green for SLNM is the preferred method. SLNM reduces the number of lymph node removal and reduces complications from lymphadenectomy without compromising oncological safety. This review discusses the latest evidence of SLNM in endometrial cancer staging in terms of technique, accuracy, limitations, impact on lymphadenectomy complications, and cancer survival.
Hong Kong J Gynaecol Obstet Midwifery 2022; 22(2):114-24
