Rapid Aneuploidy Testing, Traditional Karyotyping, or Both, in Prenatal Diagnosis Abstract

WC LEUNG, ET LAU, TT LAO, MHY TANG

The accuracy of new molecular diagnostics, fluorescence in-situ hybridisation (FISH) or quantitative fluorescence-polymerase chain reaction (QF-PCR), collectively known as rapid aneuploidy testing (RAT), in prenatal diagnosis has already been demonstrated in a number of large studies. The challenge now is how to apply them clinically in the most cost-effective manner. There is currently a hot debate in this area of prenatal diagnosis.

Hong Kong J Gynaecol Obstet Midwifery 2005; 5:33-9

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